iu.i2sysbio@uv.es (+34) 963 544 810

Introduction and objective

Joint research center of the University of Valencia and the Spanish National Research Council (CSIC), founded in 2016.

Introduction and objective

It is an institute open to the strategic participation of biotechnology companies. Its scientific programs focus on research on the structure, function, dynamics, evolution and manipulation of complex biological systems.

It aims to provide solutions to problems in the pharmaceutical, biotechnological, biomedical and agro-industrial sectors that are open to a systemic approach.

Main research programs

The research groups at ISysBio are organized thematically into five Scientific Programs (SP). These programs are dynamic and evolve to incorporate new research and developments in integrative systems biology.


  • logoTheoretical and Computational Biology
  • logoSystems Biology of Molecular Interactions and Regulation
  • logoSystems Biology of Pathogens
  • logoEvolutionary Systems Biology of Symbionts
  • logoApplied Systems Biology and Synthetic Biology
  • logoInnovation Unit (Synbiosis)

Institute for Integrative Systems Biology (UV + CSIC) news

A team from I2SysBio participates in a study that uses plants to create nanoparticles with antibodies against SARS-CoV-2
Research coordinated by Micro4Biogas group discovers bacteria that could improve biogas production
I2SysBio participates in the complete sequencing of the grapevine genome and helps design the vineyard of the future
I2SysBio team participates in the discovery of a key pea aphid gene for pest control
I2SysBio detects for the first time bacteria of pharmaceutical interest in sea slugs using a new technique
International Society for Computational Biology appoints I2SysBio researcher Ana Conesa as new Fellow

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